Gene Screening for Brain Disorders with Clinical Proof
Gene Screening for Brain Disorders with Clinical Proof
Inventions Uncover Genetics and Mechanisms Underlying Brain Developmental Disorders
Tags: National Yang Ming Chiao Tung University, Taiwan, Healthcare & Lifesciences
NYCU researchers have developed a gene screening method to identify genes involved in brain development and disorders. This method has helped discover new genes related to epilepsy, focal cortical dysplasia, and medulloblastoma, a deadly childhood brain tumor. By studying neural stem cells, the team identified mutations like CEP85L, linked to lissencephaly, a rare brain disorder. Applications of this technology include future prenatal screenings for brain disorders and potential gene therapies. This work advances both the diagnosis and treatment of brain developmental diseases.
IP Type or Form Factor: Discovery & Research; Platform
TRL: 5 - prototype ready for testing in intended environment
Industry or Tech Area: Biotechnology; Diagnostics & Screening
