Green Synthesis of Bioactive Alkanes with High Yield
Green Chemistry Method for Preparing Biologically Active Substituted Alkanes from Aldehydes and Ketones
Tags: IIT Delhi, India, Healthcare & Lifesciences, Industrial Automation & Manufacturing
A green chemistry method has been developed for synthesizing biologically active substituted alkanes using aldehydes and ketones as feedstock. This metal-free, step-economic process employs a Brønsted acid catalyst and recyclable solvents, eliminating the need for harsh reaction conditions and toxic metal complexes. The method achieves high regioselectivity and yields (69-97%), making it efficient and cost-effective. It has been successfully applied to the synthesis of bioactive natural products like Arundine and Vibrindole A. Applications include synthetic and pharmaceutical chemistry, as well as novel organic materials synthesis.
IP Type or Form Factor: Patent Pending; Process & Method
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Pharmaceutical Engineering; Sustainable Production Methods
