New Fluorescent Dye is Stable & Better Visualises Live Cells
Progress in Fluorescent Dyes to Better Visualize Lipid Membrane Order in Live Cells
Tags: Tokyo Institute of Technology, Japan, Healthcare & Lifesciences
Scientists at Tokyo Institute of Technology and Kyushu University have developed a new solvatochromic probe with high stability and low toxicity, enhancing the visualization of lipid membrane fluidity in live cells. This probe changes color based on the polarity of its environment, providing real-time insights into cellular processes like cell division. It outperforms traditional dyes with better fluorescence and longer photostability, allowing for extended observation without damaging the cells. This technology is pivotal for exploring cellular functions and could greatly benefit medical research by identifying abnormalities associated with diseases. It's especially useful in studying how lipid membrane order affects cell functionality.
IP Type or Form Factor: Material
TRL: 4 - minimum viable product built in lab
Industry or Tech Area: Biotechnology; Pharmaceutical Engineering