Silk Fibroin-Powered Cells to Replace Electronic Pacemakers
Silk Fibroin-Powered Cells to Replace Electronic Pacemakers
Silk Fibroin to Convert Quiescent Cardiomyocytes to Pacemaker Cells
Tags: National Yang Ming Chiao Tung University, Taiwan, Healthcare & Lifesciences
NYCU researchers have developed a groundbreaking method using silk fibroin (SF) to convert quiescent cardiomyocytes into pacemaker cells, restoring the heart’s natural rhythm without the need for electronic pacemakers. Injecting SF hydrogel into the hearts of mice initiated cell transformation and bioelectricity production, allowing the heart to regenerate pacemaker cells. Applications include the potential development of biological pacemakers that eliminate the need for invasive surgeries or electronic devices. The research also highlights SF's biocompatibility and versatility in medical materials, such as wound dressings and cardiac patches. This discovery offers a safer, more sustainable alternative to current pacemaker technologies.
IP Type or Form Factor: Material
TRL: 3 - proof of concept with needs validated
Industry or Tech Area: Biotechnology; Healthcare Consumer
